Assay
Age
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Immunohistochemistry (section)
3.5 DPC
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Sox2 SRY (sex determining region Y)-box 2 (Synonyms: lcc, Sox-2, ysb) | |
Results | Reference |
1* | J:310134 Adachi K, Nikaido I, Ohta H, Ohtsuka S, Ura H, Kadota M, Wakayama T, Ueda HR, Niwa H, Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells. Mol Cell. 2013 Nov 7;52(3):380-92 |
1 | J:183847 Bedzhov I, Liszewska E, Kanzler B, Stemmler MP, Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin. PLoS Genet. 2012 Mar;8(3):e1002609 |
1 | J:320718 Duethorn B, Groll F, Rieger B, Drexler HCA, Brinkmann H, Kremer L, Stehling M, Borowski MT, Mildner K, Zeuschner D, Zernicka-Goetz M, Stemmler MP, Busch KB, Vaquerizas JM, Bedzhov I, Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism. Nat Commun. 2022 Feb 1;13(1):610 |
1 | J:198640 Frum T, Halbisen MA, Wang C, Amiri H, Robson P, Ralston A, Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst. Dev Cell. 2013 Jun 24;25(6):610-22 |
1 | J:321498 Kim EJY, Sorokin L, Hiiragi T, ECM-integrin signalling instructs cellular position sensing to pattern the early mouse embryo. Development. 2022 Jan 1;149(1):dev200140 |
1* | J:337971 Kohler TN, De Jonghe J, Ellermann AL, Yanagida A, Herger M, Slatery EM, Weberling A, Munger C, Fischer K, Mulas C, Winkel A, Ross C, Bergmann S, Franze K, Chalut K, Nichols J, Boroviak TE, Hollfelder F, Plakoglobin is a mechanoresponsive regulator of naive pluripotency. Nat Commun. 2023 Jul 7;14(1):4022 |
1 | J:345904 Li L, Lai F, Liu L, Lu X, Hu X, Liu B, Lin Z, Fan Q, Kong F, Xu Q, Xie W, Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos. Nat Struct Mol Biol. 2024 Jan 19; |
1 | J:300763 Stirparo GG, Kurowski A, Yanagida A, Bates LE, Strawbridge SE, Hladkou S, Stuart HT, Boroviak TE, Silva JCR, Nichols J, OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2008890118 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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